Drawing in the example of physiology, the introduction argues in favour of combining approaches from the history science with conceptual tools derived from media studies. In the wake of Gilles Deleuze and Félix Guattari, it aims at establishing a machine-centred approach to the history of scientific and artistic innovation. At the same time, it is argued that situated research machines have to be contextualized with respect to large technical systems, e.g. telegraphy.
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